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Oral nicotine aggravates endothelial dysfunction and vascular inflammation in diet-induced obese rats: Role of macrophage TNFα

Obesity and cigarette smoke are major cardiovascular (CV) risk factors and, when coexisting in the same individuals, have additive/synergistic effects upon CVD. We studied the mechanisms involved in nicotine enhancement of CVD in Sprague Dawley rats with diet–induced obesity. The rats were fed eithe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Chang, Zhou, Ming-Sheng, Li, Yao, Wang, Aimei, Chadipiralla, Kiranmai, Tian, Runxia, Raij, Leopoldo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728478/
https://ncbi.nlm.nih.gov/pubmed/29236702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188439
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