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Carbachol inhibits TNF-α-induced endothelial barrier dysfunction through alpha 7 nicotinic receptors

AIM: To test whether carbachol can influence endothelial barrier dysfunction induced by tumor necrosis factor (TNF)-α and whether the alpha 7 nicotinic receptor can mediate this process. METHODS: Rat cardiac microvascular endothelial cells were exposed to carbachol followed by TNF-α treatment in the...

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Detalhes bibliográficos
Main Authors: Li, Yu-zhen, Liu, Xiu-hua, Rong, Fei, Hu, Sen, Sheng, Zhi-yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012914/
https://ncbi.nlm.nih.gov/pubmed/20871620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.165
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