Near-tetraploidy is associated with Richter transformation in chronic lymphocytic leukemia patients receiving ibrutinib

Ibrutinib is a highly effective targeted therapy for chronic lymphocytic leukemia (CLL). However, ibrutinib must be discontinued in a subset of patients due to progressive CLL or transformation to aggressive lymphoma (Richter transformation). Transformation occurs early in the course of therapy and...

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書目詳細資料
發表在:Blood Adv
Main Authors: Miller, Cecelia R., Ruppert, Amy S., Heerema, Nyla A., Maddocks, Kami J., Labanowska, Jadwiga, Breidenbach, Heather, Lozanski, Gerard, Zhao, Weiqiang, Gordon, Amber L., Jones, Jeffrey A., Flynn, Joseph M., Jaglowski, Samantha M., Andritsos, Leslie A., Blum, Kristie A., T. Awan, Farrukh, Rogers, Kerry A., Grever, Michael R., Johnson, Amy J., Abruzzo, Lynne V., Hertlein, Erin K., Blachly, James S., Woyach, Jennifer A., Byrd, John C.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2017
主題:
Clinical Trials and Observations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728464/
https://ncbi.nlm.nih.gov/pubmed/29296799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007302
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