載入...
TG02 inhibits proteasome inhibitor–induced HSF1 serine 326 phosphorylation and heat shock response in multiple myeloma
Proteasome inhibition activates multiple kinases in myeloma cells resulting in the phosphorylation of p53, HSP27, c-JUN, and HSF1. TG02 inhibits proteasome inhibitor (PI)–induced HSF1 pS326, representing a novel mechanism for a TG02 and PI combination.
Na minha lista:
| 發表在: | Blood Adv |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728095/ https://ncbi.nlm.nih.gov/pubmed/29296831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006122 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|