Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia

The oncogenic mechanisms driven by aberrantly expressed transcription factors in T-cell acute leukemia (T-ALL) are still elusive. MicroRNAs (miRNAs) play an important role in normal development and pathologies. Here, we examined the expression of 738 miRNA species in 41 newly diagnosed pediatric T-A...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Renou, Laurent, Boelle, Pierre-Yves, Deswarte, Caroline, Spicuglia, Salvatore, Benyoucef, Aissa, Calvo, Julien, Uzan, Benjamin, Belhocine, Mohamed, Cieslak, Agata, Landman-Parker, Judith, Baruchel, Andre, Asnafi, Vahid, Pflumio, Françoise, Ballerini, Paola, Naguibneva, Irina
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728055/
https://ncbi.nlm.nih.gov/pubmed/29296717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017005538
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