Quantification of HTLV-1 reverse transcriptase activity in ATL patients treated with zidovudine and interferon-α

The therapeutic efficacy of the AZT and IFN combination in ATL presumably reflects the inhibition of RT-related functions. HTLV-1–RT activity from short-term cultured PBMCs may represent a predictive correlate of clinical response to AZT/IFN in ATL patients.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Macchi, Beatrice, Balestrieri, Emanuela, Frezza, Caterina, Grelli, Sandro, Valletta, Elena, Marçais, Ambroise, Marino-Merlo, Francesca, Turpin, Jocelyn, Bangham, Charles R., Hermine, Olivier, Mastino, Antonio, Bazarbachi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Stimulus Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728049/
https://ncbi.nlm.nih.gov/pubmed/29296718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016001370
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