Inhibition of IκBα phosphorylation potentiates regulated cell death induced by azidothymidine in HTLV-1 infected cells

Adult T cell leukemia/lymphoma (ATL) can be susceptible, at least transiently, to treatments with azidothymidine (AZT) plus IFNα and/or arsenic trioxide. However, the real role of AZT in this effect is still unclear. In fact, while reverse transcriptase (RT) inhibition could explain reduction of clo...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Matteucci, Claudia, Marino-Merlo, Francesca, Minutolo, Antonella, Balestrieri, Emanuela, Valletta, Elena, Macchi, Beatrice, Mastino, Antonio, Grelli, Sandro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028944/
https://ncbi.nlm.nih.gov/pubmed/32123585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0243-x
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