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Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients

BACKGROUND: The HER2-HER3 heterodimer significantly decreases survival in breast cancer patients. However, the prognostic value of HER2-HER3 overexpression remains unknown in gastric cancer (GC). METHODS: The expression levels of HER2, HER3, Akt, p-Akt, mTOR and p-mTOR were examined in specimens fro...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Cao, Guo-dong, Chen, Ke, Chen, Bo, Xiong, Mao-ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727869/
https://ncbi.nlm.nih.gov/pubmed/29233126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3851-y
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