Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor–Positive, HER2-Negative Early Breast Cancer()

BACKGROUND: The PI3K/AKT/mTOR pathway alterations have been shown to play significant roles in the development, progression, and metastatic spread of breast cancer. Furthermore, they have been implicated in the process of drug resistance, especially endocrinal therapies. In this study, we aimed to d...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Azim, Hamdy A., Kassem, Loay, Treilleux, Isabelle, Wang, Qing, El Enein, Mona Abu, Anis, Shady E., Bachelot, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2016
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833894/
https://ncbi.nlm.nih.gov/pubmed/27084427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2016.01.001
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