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The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis

BACKGROUND: Osteoarthritis (OA) is a chronic joint disease and there is no a definitive cure at present. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in the development of OA. However, the underlying mechanism of lncRNA maternally expressed gene 3 (MEG3) in OA has not b...

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Pubblicato in:Cell Biosci
Autori principali: Xu, Jin, Xu, Yaozeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727780/
https://ncbi.nlm.nih.gov/pubmed/29255591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0195-x
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