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LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation

BACKGROUND: Our preliminary RNA-Seq data revealed altered expression of small nucleolar RNA host gene 9 (SNHG9) in osteoarthritis (OA) and its reverse correlation with miR-34a, which can regulate chondrocyte apoptosis in rat OA model. This study was therefore carried out to investigate the potential...

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Bibliografische gegevens
Gepubliceerd in:BMC Musculoskelet Disord
Hoofdauteurs: Zhang, Hongfei, Li, Jinglian, Shao, Weiguang, Shen, Naipeng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395373/
https://ncbi.nlm.nih.gov/pubmed/32738890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-020-03497-7
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