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Association of MTHFR C677T and A1298C gene polymorphisms with methotrexate efficiency and toxicity in Algerian rheumatoid arthritis patients

Methotrexate (MTX) is the most used drug in rheumatoid arthritis (RA) treatment. However, it shows variability in clinical response, which is explained by an association with genetic polymorphisms. This study aimed to elucidate the role of the two gene polymorphism C677T and A1298C of the methylenet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Heliyon
Egile Nagusiak: Berkani, Lilya M., Rahal, Fadia, Allam, Ines, Mouaki Benani, Soraya, Laadjouz, Aïcha, Djidjik, Reda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727549/
https://ncbi.nlm.nih.gov/pubmed/29264421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00467
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