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An optogenetic arrhythmia model to study catecholaminergic polymorphic ventricular tachycardia mutations
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition of abnormal heart rhythm (arrhythmia), induced by physical activity or stress. Mutations in ryanodine receptor 2 (RyR2), a Ca(2+) release channel located in the sarcoplasmic reticulum (SR), or calsequestrin 2 (CASQ2), a SR C...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727474/ https://ncbi.nlm.nih.gov/pubmed/29235522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17819-8 |
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