Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P

Gene-specific expansion of the genetic code allows for UGA codons to specify the amino acid selenocysteine (Sec). A striking example of UGA redefinition occurs during translation of the mRNA coding for the selenium transport protein, selenoprotein P (SELENOP), which in vertebrates may contain up to...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Mariotti, Marco, Shetty, Sumangala, Baird, Lisa, Wu, Sen, Loughran, Gary, Copeland, Paul R., Atkins, John F., Howard, Michael T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
RNA and RNA-protein complexes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727441/
https://ncbi.nlm.nih.gov/pubmed/29069514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx982
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