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Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA

Imprinted genes occur in discrete clusters that are coordinately regulated by shared DNA elements called Imprinting Control Regions. H19 and Igf2 are linked imprinted genes that play critical roles in development. Loss of imprinting (LOI) at the IGF2/H19 locus on the maternal chromosome is associate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Park, Ki-Sun, Mitra, Apratim, Rahat, Beenish, Kim, Keekwang, Pfeifer, Karl
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727439/
https://ncbi.nlm.nih.gov/pubmed/29244185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx896
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