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Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA
Imprinted genes occur in discrete clusters that are coordinately regulated by shared DNA elements called Imprinting Control Regions. H19 and Igf2 are linked imprinted genes that play critical roles in development. Loss of imprinting (LOI) at the IGF2/H19 locus on the maternal chromosome is associate...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727439/ https://ncbi.nlm.nih.gov/pubmed/29244185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx896 |
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