Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation

Transposable elements, including endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome. They are transcriptionally silenced during early development to protect genome integrity and aberrant transcription. However, the mechanisms that control their repression are not ful...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Li, Pishun, Wang, Li, Bennett, Brian D., Wang, Jiajia, Li, Jialun, Qin, Yufeng, Takaku, Motoki, Wade, Paul A., Wong, Jiemin, Hu, Guang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727408/
https://ncbi.nlm.nih.gov/pubmed/29040764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx884
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