Infection via mosquito bite alters Zika virus tissue tropism and replication kinetics in rhesus macaques

Mouse and nonhuman primate models now serve as useful platforms to study Zika virus (ZIKV) pathogenesis, candidate therapies, and vaccines, but they rely on needle inoculation of virus: the effects of mosquito-borne infection on disease outcome have not been explored in these models. Here we show th...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Dudley, Dawn M., Newman, Christina M., Lalli, Joseph, Stewart, Laurel M., Koenig, Michelle R., Weiler, Andrea M., Semler, Matthew R., Barry, Gabrielle L., Zarbock, Katie R., Mohns, Mariel S., Breitbach, Meghan E., Schultz-Darken, Nancy, Peterson, Eric, Newton, Wendy, Mohr, Emma L., Capuano III, Saverio, Osorio, Jorge E., O’Connor, Shelby L., O’Connor, David H., Friedrich, Thomas C., Aliota, Matthew T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727388/
https://ncbi.nlm.nih.gov/pubmed/29235456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02222-8
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