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BIO 300, a nanosuspension of genistein, mitigates pneumonitis/fibrosis following high‐dose radiation exposure in the C57L/J murine model

BACKGROUND AND PURPOSE: BIO 300 nanosuspension (Humanetics Corporation) is being developed as a medical countermeasure (MCM) for the mitigation of the delayed effects of acute radiation exposure, specifically pneumonitis and fibrosis of the lung. The objective of this study was to determine the best...

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Pubblicato in:Br J Pharmacol
Autori principali: Jackson, Isabel L, Zodda, Andrew, Gurung, Ganga, Pavlovic, Radmila, Kaytor, Michael D, Kuskowski, Michael A, Vujaskovic, Zeljko
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727338/
https://ncbi.nlm.nih.gov/pubmed/28963717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14056
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