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Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model

Genistein is a naturally occurring phytoestrogen isoflavone and is the active drug ingredient in BIO 300, a radiation countermeasure under advanced development for acute radiation syndrome (H-ARS) and for the delayed effects of acute radiation exposure (DEARE). Here we have assessed the pharmacokine...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cheema, Amrita K., Mehta, Khyati Y., Santiago, Paola T., Fatanmi, Oluseyi O., Kaytor, Michael D., Singh, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429499/
https://ncbi.nlm.nih.gov/pubmed/30870965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051231
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