Tear proteome analysis in ocular surface diseases using label-free LC-MS/MS and multiplexed-microarray biomarker validation

We analyzed the tear film proteome of patients with dry eye (DE), meibomian gland dysfunction (MGD), and normal volunteers (CT). Tear samples were collected from 70 individuals. Of these, 37 samples were analyzed using spectral-counting-based LC-MS/MS label-free quantitation, and 33 samples were eva...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Soria, Javier, Acera, Arantxa, Merayo-LLoves, Jesús, Durán, Juan A., González, Nerea, Rodriguez, Sandra, Bistolas, Nikitas, Schumacher, Soeren, Bier, Frank F., Peter, Harald, Stöcklein, Walter, Suárez, Tatiana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727318/
https://ncbi.nlm.nih.gov/pubmed/29234088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17536-2
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