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The Development of Target-Specific Pose Filter Ensembles To Boost Ligand Enrichment for Structure-Based Virtual Screening

Structure-based virtual screening (SBVS) has become an indispensable technique for hit identification at the early stage of drug discovery. However, the accuracy of current scoring functions is not high enough to confer success to every target and thus remains to be improved. Previously, we had deve...

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Xia, Jie, Hsieh, Jui-Hua, Hu, Huabin, Wu, Song, Wang, Xiang Simon
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726860/
https://ncbi.nlm.nih.gov/pubmed/28511009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.6b00749
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