Cell invasion in vivo via rapid exocytosis of a transient lysosome-derived membrane domain

Invasive cells use small invadopodia to breach basement membrane (BM), a dense matrix that encases tissues. Following the breach, a large protrusion forms to clear a path for tissue entry by poorly understood mechanisms. Using RNAi screening for defects in C. elegans anchor cell (AC) invasion, we fo...

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Udgivet i:Dev Cell
Main Authors: Naegeli, Kaleb M., Hastie, Eric, Garde, Aastha, Wang, Zheng, Keeley, Daniel P., Gordon, Kacy L., Pani, Ariel M., Kelley, Laura C., Morrissey, Meghan A., Chi, Qiuyi, Goldstein, Bob, Sherwood, David R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726793/
https://ncbi.nlm.nih.gov/pubmed/29161591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.10.024
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