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Dependence of prevalence of contiguous pathways in proteins on structural complexity

Allostery is a regulatory mechanism in proteins where an effector molecule binds distal from an active site to modulate its activity. Allosteric signaling may occur via a continuous path of residues linking the active and allosteric sites, which has been suggested by large conformational changes evi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thayer, Kelly M., Galganov, Jesse C., Stein, Avram J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726733/
https://ncbi.nlm.nih.gov/pubmed/29232711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188616
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