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A computational model for regulation of nanoscale glucan exposure in Candida albicans

Candida albicans is a virulent human opportunistic pathogen. It evades innate immune surveillance by masking an immunogenic cell wall polysaccharide, β-glucan, from recognition by the immunoreceptor Dectin-1. Glucan unmasking by the antifungal drug caspofungin leads to changes in the nanostructure o...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Wester, Michael J., Lin, Jia, Neumann, Aaron K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726713/
https://ncbi.nlm.nih.gov/pubmed/29232689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188599
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