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Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL

Protein–carbohydrate interactions are very often mediated by the stacking CH–π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe). Especially suitable for stacking is the Trp residue. Analysis of the PDB database shows Trp s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Houser, Josef, Kozmon, Stanislav, Mishra, Deepti, Mishra, Sushil K., Romano, Patrick R., Wimmerová, Michaela, Koča, Jaroslav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726637/
https://ncbi.nlm.nih.gov/pubmed/29232414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189375
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