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Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL

Protein–carbohydrate interactions are very often mediated by the stacking CH–π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe). Especially suitable for stacking is the Trp residue. Analysis of the PDB database shows Trp s...

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Veröffentlicht in:PLoS One
Hauptverfasser: Houser, Josef, Kozmon, Stanislav, Mishra, Deepti, Mishra, Sushil K., Romano, Patrick R., Wimmerová, Michaela, Koča, Jaroslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726637/
https://ncbi.nlm.nih.gov/pubmed/29232414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189375
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