Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

PURPOSE: Women at familial/genetic ovarian cancer risk often undergo screening despite unproven efficacy. Research suggests each woman has her own CA125 baseline; significant increases above this level may identify cancers earlier than standard 6–12 monthly CA125>35U/mL. EXPERIMENTAL DESIGN: Data...

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Udgivet i:Clin Cancer Res
Main Authors: Skates, Steven J., Greene, Mark H., Buys, Saundra S., Mai, Phuong L., Brown, Powel, Piedmonte, Marion, Rodriguez, Gustavo, Schorge, John O., Sherman, Mark, Daly, Mary B., Rutherford, Thomas, Brewster, Wendy R., O’Malley, David M., Partridge, Edward, Boggess, John, Drescher, Charles W., Isaacs, Claudine, Berchuck, Andrew, Domchek, Susan, Davidson, Susan A., Edwards, Robert, Elg, Steven A., Wakeley, Katie, Phillips, Kelly-Anne, Armstrong, Deborah, Horowitz, Ira, Fabian, Carol J., Walker, Joan, Sluss, Patrick M., Welch, William, Minasian, Lori, Horick, Nora K., Kasten, Carol H., Nayfield, Susan, Alberts, David, Finkelstein, Dianne M., Lu, Karen H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726402/
https://ncbi.nlm.nih.gov/pubmed/28143870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2750
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