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Large Prospective Study of Ovarian Cancer Screening in High-risk Women: CA125 Cut-point Defined by Menopausal Status

BACKGROUND: Previous screening trials for early detection of ovarian cancer in postmenopausal women have used the standard CA125 cut-point of 35 U/mL, the 98(th) percentile in this population yielding a 2% false positive rate, while the same cut-point in trials of premenopausal women results in subs...

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Autores principales: Skates, Steven J., Mai, Phuong, Horick, Nora K., Piedmonte, Marion, Drescher, Charles W., Isaacs, Claudine, Armstrong, Deborah K., Buys, Saundra S., Rodriguez, Gustavo C., Horowitz, Ira R., Berchuck, Andrew, Daly, Mary B., Domchek, Susan, Cohn, David E., Van Le, Linda, Schorge, John O., Newland, William, Davidson, Susan A., Barnes, Mack, Brewster, Wendy, Azodi, Masoud, Nerenstone, Stacy, Kauff, Noah D., Fabian, Carol J., Sluss, Patrick M., Nayfield, Susan G., Kasten, Carol H., Finkelstein, Dianne M., Greene, Mark H., Lu, Karen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172691/
https://ncbi.nlm.nih.gov/pubmed/21893500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0402
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