Large Prospective Study of Ovarian Cancer Screening in High-risk Women: CA125 Cut-point Defined by Menopausal Status

BACKGROUND: Previous screening trials for early detection of ovarian cancer in postmenopausal women have used the standard CA125 cut-point of 35 U/mL, the 98(th) percentile in this population yielding a 2% false positive rate, while the same cut-point in trials of premenopausal women results in subs...

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Main Authors: Skates, Steven J., Mai, Phuong, Horick, Nora K., Piedmonte, Marion, Drescher, Charles W., Isaacs, Claudine, Armstrong, Deborah K., Buys, Saundra S., Rodriguez, Gustavo C., Horowitz, Ira R., Berchuck, Andrew, Daly, Mary B., Domchek, Susan, Cohn, David E., Van Le, Linda, Schorge, John O., Newland, William, Davidson, Susan A., Barnes, Mack, Brewster, Wendy, Azodi, Masoud, Nerenstone, Stacy, Kauff, Noah D., Fabian, Carol J., Sluss, Patrick M., Nayfield, Susan G., Kasten, Carol H., Finkelstein, Dianne M., Greene, Mark H., Lu, Karen
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172691/
https://ncbi.nlm.nih.gov/pubmed/21893500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0402
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