Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population

BACKGROUND: Evaluation of interindividual variability is a challenging step in risk assessment. For most environmental pollutants, including perchloroethylene (PERC), experimental data are lacking, resulting in default assumptions being used to account for variability in toxicokinetics and toxicodyn...

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Publicado en:Environ Health Perspect
Autores principales: Cichocki, Joseph A., Furuya, Shinji, Venkatratnam, Abhishek, McDonald, Thomas J., Knap, Anthony H., Wade, Terry, Sweet, Stephen, Chiu, Weihsueh A., Threadgill, David W., Rusyn, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: Environmental Health Perspectives 2017
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726344/
https://ncbi.nlm.nih.gov/pubmed/28572074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP788
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