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Transgene expression in the genome of Middle East respiratory syndrome coronavirus based on a novel reverse genetics system utilizing Red-mediated recombination cloning

Middle East respiratory syndrome coronavirus (MERS-CoV) is a high-priority pathogen in pandemic preparedness research. Reverse genetics systems are a valuable tool to study viral replication and pathogenesis, design attenuated vaccines and create defined viral assay systems for applications such as...

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Dades bibliogràfiques
Publicat a:J Gen Virol
Autors principals: Muth, Doreen, Meyer, Benjamin, Niemeyer, Daniela, Schroeder, Simon, Osterrieder, Nikolaus, Müller, Marcel Alexander, Drosten, Christian
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725994/
https://ncbi.nlm.nih.gov/pubmed/28984231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000919
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