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Exploiting Uniformly (13)C-Labeled Carbohydrates for Probing Carbohydrate-Protein Interactions by NMR Spectroscopy
NMR of a uniformly (13)C-labeled carbohydrate was used to elucidate the atomic details of a sugar-protein complex. The structure of the (13)C-labeled Manα(1–2)Manα(1–2)ManαOMe trisaccharide ligand when bound to cyanovirin-N was characterized and revealed that in the complex the glycosidic linkage to...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725960/ https://ncbi.nlm.nih.gov/pubmed/28406013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01929 |
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