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A simple and accurate rule-based modeling framework for simulation of autocrine/paracrine stimulation of glioblastoma cell motility and proliferation by L1CAM in 2-D culture

BACKGROUND: Glioblastoma multiforme (GBM) is a devastating brain cancer for which there is no known cure. Its malignancy is due to rapid cell division along with high motility and invasiveness of cells into the brain tissue. Simple 2-dimensional laboratory assays (e.g., a scratch assay) commonly are...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Syst Biol
Main Authors: Caccavale, Justin, Fiumara, David, Stapf, Michael, Sweitzer, Liedeke, Anderson, Hannah J., Gorky, Jonathan, Dhurjati, Prasad, Galileo, Deni S.
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725844/
https://ncbi.nlm.nih.gov/pubmed/29228953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0516-z
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