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Silica inhalation altered telomere length and gene expression of telomere regulatory proteins in lung tissue of rats

Exposure to silica can cause lung fibrosis and cancer. Identification of molecular targets is important for the intervention and/or prevention of silica-induced lung diseases. Telomeres consist of tandem repeats of DNA sequences at the end of chromosomes, preventing chromosomal fusion and degradatio...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Shoeb, Mohammad, Joseph, Pius, Kodali, Vamsi, Mustafa, Gul, Farris, Breanne Y., Umbright, Christina, Roberts, Jenny R., Erdely, Aaron, Antonini, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725592/
https://ncbi.nlm.nih.gov/pubmed/29230030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17645-y
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