Chemoinformatics Profiling of the Chromone Nucleus as a MAO-B/A(2A)AR Dual Binding Scaffold

BACKGROUND: In the context of the current drug discovery efforts to find disease modifying therapies for Parkinson´s disease (PD) the current single target strategy has proved inefficient. Consequently, the search for multi-potent agents is attracting more and more attention due to the multiple path...

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Vydáno v:Curr Neuropharmacol
Hlavní autoři: Cruz-Monteagudo, Maykel, Borges, Fernanda, Cordeiro, M. Natália D. S., Helguera, Aliuska Morales, Tejera, Eduardo, Paz-y-Miño, Cesar, Sánchez-Rodríguez, Aminael, Perera-Sardiña, Yunier, Perez-Castillo, Yunierkis
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Science Publishers 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725544/
https://ncbi.nlm.nih.gov/pubmed/28093976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X15666170116145316
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