Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation

The accumulation of visceral adiposity is strongly associated with systemic inflammation and increased cardiometabolic risk. WNT5A, a non-canonical WNT ligand, has been shown to promote adipose tissue inflammation and insulin resistance in animal studies. Among other non-canonical pathways, WNT5A ac...

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Publicat a:Sci Rep
Autors principals: Zuriaga, María A., Fuster, José J., Farb, Melissa G., MacLauchlan, Susan, Bretón-Romero, Rosa, Karki, Shakun, Hess, Donald T., Apovian, Caroline M., Hamburg, Naomi M., Gokce, Noyan, Walsh, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725530/
https://ncbi.nlm.nih.gov/pubmed/29229927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17509-5
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