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Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation
The accumulation of visceral adiposity is strongly associated with systemic inflammation and increased cardiometabolic risk. WNT5A, a non-canonical WNT ligand, has been shown to promote adipose tissue inflammation and insulin resistance in animal studies. Among other non-canonical pathways, WNT5A ac...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725530/ https://ncbi.nlm.nih.gov/pubmed/29229927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17509-5 |
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