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Metabolic re-patterning in COPD airway smooth muscle cells

Chronic obstructive pulmonary disease (COPD) airways are characterised by thickening of airway smooth muscle, partly due to airway smooth muscle cell (ASMC) hyperplasia. Metabolic reprogramming involving increased glycolysis and glutamine catabolism supports the biosynthetic and redox balance requir...

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Détails bibliographiques
Publié dans:Eur Respir J
Auteurs principaux: Michaeloudes, Charalambos, Kuo, Chih-Hsi, Haji, Gulam, Finch, Donna K., Halayko, Andrew J., Kirkham, Paul, Chung, Kian Fan, Adcock, Ian M.
Format: Artigo
Langue:Inglês
Publié: European Respiratory Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725208/
https://ncbi.nlm.nih.gov/pubmed/29191950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00202-2017
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