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Metabolic re-patterning in COPD airway smooth muscle cells

Chronic obstructive pulmonary disease (COPD) airways are characterised by thickening of airway smooth muscle, partly due to airway smooth muscle cell (ASMC) hyperplasia. Metabolic reprogramming involving increased glycolysis and glutamine catabolism supports the biosynthetic and redox balance requir...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Michaeloudes, Charalambos, Kuo, Chih-Hsi, Haji, Gulam, Finch, Donna K., Halayko, Andrew J., Kirkham, Paul, Chung, Kian Fan, Adcock, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725208/
https://ncbi.nlm.nih.gov/pubmed/29191950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00202-2017
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