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Role of Dopamine Receptors in the Anticancer Activity of ONC201()()
ONC201/TIC10 is a first-in-class small molecule inducer of TRAIL that causes early activation of the integrated stress response. Its promising safety profile and broad-spectrum efficacy in vitro have been confirmed in Phase I/II trials in several advanced malignancies. Binding and reporter assays ha...
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| Izdano u: | Neoplasia |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Neoplasia Press
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725157/ https://ncbi.nlm.nih.gov/pubmed/29216597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.10.002 |
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