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Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets

Recent advances in chemotherapeutics highlight the importance of molecularly-targeted perturbagens. Although these therapies typically address dysregulated cancer cell proteins, there are increasing therapeutic modalities that take into consideration cancer cell-extrinsic factors. Targeting componen...

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Vydáno v:Oncotarget
Hlavní autoři: Horman, Shane R., To, Jeremy, Lamb, John, Zoll, Jocelyn H., Leonetti, Nicole, Tu, Buu, Moran, Rita, Newlin, Robbin, Walker, John R., Orth, Anthony P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725140/
https://ncbi.nlm.nih.gov/pubmed/29245949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21915
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