A genomic screen identifies TYRO3 as a MITF regulator in melanoma

Malignant melanoma is the most aggressive form of cutaneous carcinoma, accounting for 75% of all deaths caused by skin cancers. Microphthalmia-associated transcription factor (MITF) is a master gene regulating melanocyte development and functions as a “lineage addiction” oncogene in malignant melano...

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Main Authors: Zhu, Shoutian, Wurdak, Heiko, Wang, Yan, Galkin, Anna, Tao, Haiyan, Li, Jie, Lyssiotis, Costas A., Yan, Feng, Tu, Buu P., Miraglia, Loren, Walker, John, Sun, Fanxiang, Orth, Anthony, Schultz, Peter G., Wu, Xu
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761329/
https://ncbi.nlm.nih.gov/pubmed/19805117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909292106
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