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Mesenchymal stem cells inhibit T cell activation by releasing TGF-β1 from TGF-β1/GARP complex

Intervention with mesenchymal stem cells (MSCs) reveals a promising therapeutic tool to treat transplantation and autoimmune disease due to their immunoregulation capability. But the mechanisms of action are not fully investigated yet. Transforming growth factor-β1 (TGF-β1) exhibit multiple effects...

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Pubblicato in:Oncotarget
Autori principali: Niu, Jian, Yue, Wang, Le-Le, Zhu, Bin, Liu, Hu, Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725131/
https://ncbi.nlm.nih.gov/pubmed/29245940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21549
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