NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

Gliomas are the most prevalent primary malignant brain tumors associated with poor prognosis. NAMPT, a rate-limiting enzyme that boosts the nicotinamide adenine dinucleotide (NAD) regeneration in the salvage pathway, is commonly expressed in these tumors. NAD metabolism is required to maintain tissu...

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Udgivet i:Oncotarget
Main Authors: Lucena-Cacace, Antonio, Otero-Albiol, Daniel, Jiménez-García, Manuel P., Peinado-Serrano, Javier, Carnero, Amancio
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725111/
https://ncbi.nlm.nih.gov/pubmed/29245920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20577
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