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NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis
Gliomas are the most prevalent primary malignant brain tumors associated with poor prognosis. NAMPT, a rate-limiting enzyme that boosts the nicotinamide adenine dinucleotide (NAD) regeneration in the salvage pathway, is commonly expressed in these tumors. NAD metabolism is required to maintain tissu...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725111/ https://ncbi.nlm.nih.gov/pubmed/29245920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20577 |
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