Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

Recent evidence suggests that the metastatic spread of head and neck squamous cell carcinomas (HNSCC) requires the function of cancer stem cells endowed with multipotency, self-renewal, and high tumorigenic potential. We demonstrated that cancer stem cells reside in perivascular niches and are chara...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Kim, Hong Sun, Chen, Yu-Chih, Nör, Felipe, Warner, Kristy A., Andrews, April, Wagner, Vivian P., Zhang, Zhaocheng, Zhang, Zhixiong, Martins, Manoela D., Pearson, Alexander T., Yoon, Euisik, Nör, Jacques E.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725024/
https://ncbi.nlm.nih.gov/pubmed/29245982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22225
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