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Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

Recent evidence suggests that the metastatic spread of head and neck squamous cell carcinomas (HNSCC) requires the function of cancer stem cells endowed with multipotency, self-renewal, and high tumorigenic potential. We demonstrated that cancer stem cells reside in perivascular niches and are chara...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Hong Sun, Chen, Yu-Chih, Nör, Felipe, Warner, Kristy A., Andrews, April, Wagner, Vivian P., Zhang, Zhaocheng, Zhang, Zhixiong, Martins, Manoela D., Pearson, Alexander T., Yoon, Euisik, Nör, Jacques E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725024/
https://ncbi.nlm.nih.gov/pubmed/29245982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22225
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