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CSNAP is a stoichiometric subunit of the COP9 signalosome

The highly conserved COP9 signalosome (CSN) complex is a key regulator of all cullin-RING-ubiquitin ligases (CRLs), the largest family of E3 ubiquitin ligases. Until now it was accepted that the CSN is comprised of eight canonical components. Here, we report the discovery of an additional integral a...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Rozen, Shelly, Füzesi -Levi, Maria G., Ben-Nissan, Gili, Mizrachi, Limor, Gabashvili, Alexandra, Levin, Yishai, Ben-Dor, Shifra, Eisenstein, Miriam, Sharon, Michal
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724754/
https://ncbi.nlm.nih.gov/pubmed/26456823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.021
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