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Initial evaluation of Cu-64 labeled PARPi-DOTA PET imaging in mice with mesothelioma

Poly(ADP-ribose) polymerase (PARP) has emerged as an important molecular target for the treatment of several oncological diseases. A couple of molecular probes based on Olaparib scaffold have been developed by incorporation of F-18 or fluorophore for positron emission tomography (PET) or optical ima...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem Lett
Hoofdauteurs: Huang, Tao, Hu, Pengcheng, Banizs, Anna B., He, Jiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724367/
https://ncbi.nlm.nih.gov/pubmed/28587822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.05.077
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